Screening of Immunostimulatory Activity from Indonesian Kampung (Gallus domesticus) Egg White Water Extract: in vitro study

The most popular Indonesian native chicken, known as kampung is maintained under free-range conditions therefore it prone to high environmental stress. chicken and its product are always regarded having health benefits compared commercial by society. But there still limited report regarding product. This study focused on screening immunostimulatory activity from egg white using in vitro approaches a functional food. (NEW) was extracted distilled water supplemented human-human hybridoma HB4C5 cells examine the IgM production stimulating ELISA. gene expression also examined qRT-PCR. ability of NEW immunoglobulin mouse splenocytes analyzed. Commercial extract (CEW) used comparison. data were analyzed One-way ANOVA continued post-hoc analysis Tukey’s multiple comparison test. results showed that CEW modulated 8.72-fold 6.75-fold, respectively, control. stimulated (Ig) higher than CEW. To conclude, provides an immunostimulating can potentially act health-promoting